EGFR-IN-49
Product Specifications
CAS Number
2459932-81-9
Target
Others|||EGFR
Related Pathways
Tyrosine Kinase/Adaptors|||JAK/STAT signaling|||Angiogenesis|||Others
Bioactivity
EGFR-IN-49 is a potent and selective EGFR inhibitor that targets EGFRT790M (IC50: 65.0 nM) and EGFRT790M/L858R (IC50: 13.6 nM), inducing apoptosis in a dose-dependent manner.
Smiles
O(C1=C2C(=NC(NC3=CC(C#N)=CC=C3)=N1)C=CS2)C4=CC(NC(C=C)=O)=CC=C4
Molecular Formula
C22H15N5O2S
Molecular Weight
413.45
Shipping Conditions
Cool pack
Storage Temperature
-20°C
Available Sizes
Curated Selection
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