C-ABL-IN-4
Product Specifications
CAS Number
2626934-68-5
Target
Others, Bcr-Abl
Related Pathways
Angiogenesis, Tyrosine Kinase/Adaptors, Cytoskeletal Signaling, Others
Bioactivity
C-ABL-IN-4, a potent inhibitor of c-Abl, exhibits strong activity in inhibiting the Bcr-Abl (IC50 = 4.5 nM) kinase activity and proliferation (IC50 = 0.41-2.12 μM) of Bcr-Abl (T315I) cell lines.
Smiles
O=C1N(C=C(C(NC2=CC=C(OC(Cl)(F)F)C=C2)=O)C=C1)C=3C=C(F)C=NC3
Molecular Formula
C18H11ClF3N3O3
Molecular Weight
409.75
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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