PDE4B/7A-IN-2
Product Specifications
CAS Number
2511632-55-4
Target
Others, PDE
Related Pathways
Others, Metabolism
Bioactivity
This compound is a dual 5-HT1A/5-HT7 receptor antagonist (5-HT1A Ki = 8 nM, Kb = 0.04 nM; 5-HT7 Ki = 451 nM, Kb = 460 nM) with additional inhibitory activity against PDE4B/PDE7A (PDE4B IC50 = 80.4 μM; PDE7A IC50 = 151.3 μM) . Its antidepressant-like effect surpasses that of the reference agent, escitalopram.
Smiles
O(C)C1=C(C=CC=C1)N2CCN(CCCCC(NC3=CC=C(C(C)C)C=C3)=O)CC2
Molecular Formula
C25H35N3O2
Molecular Weight
409.56
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
More Discoveries
Explore Other Products
Browse additional items from our catalog
sc-391358 100 mg
(2S,3S) -3-Benzyloxycarbonylamino-2-methyl-4-oxo-1-azetidinesulfonic Acid Tetrabutylammonium Salt
Sign In for Pricing
View Details 
PA2228-Biotin 100 µg/Vial
Anti-Phospholipid transfer protein PLTP Antibody Picoband® (Biotine Conjugate)
Sign In for Pricing
View Details orb2411924 100 µL
Phospho-GABBR2 (Ser892) Rabbit Polyclonal Antibody (BF488)
Sign In for Pricing
View Details ![Mouse Monoclonal Herpes Simplex Virus UL42 Antibody (13D11) [mFluor Violet 450 SE]](https://cdn.genprice.uk/genprice/uk/genprice2.webp)
NB100-2772MFV450 0.1 mL
Mouse Monoclonal Herpes Simplex Virus UL42 Antibody (13D11) [mFluor Violet 450 SE]
Sign In for Pricing
View Details 588485 50 µg
KIAA1618 (Ring Finger Protein 213, C17orf27, KIAA1554)
Sign In for Pricing
View Details