NF-?B-IN-5
Product Specifications
CAS Number
2425675-52-9
Target
Others|||Apoptosis|||NF-?B
Related Pathways
Others|||NF-?B|||Apoptosis
Bioactivity
NF-?B-IN-5 (compound 4d) is an orally active NF-?B inhibitor that interacts directly with NF-?B, and exhibits antitumor activity against human cancer cell lines, with IC50 values of 5.35, 2.81, 2.83, 2.02, and 3.90 ?M for HCT116, U87-MG, HepG2, BGC823, and PC9, respectively.
Smiles
C[C@]12[C@@]([C@@]3([C@](C(=C)C(=O)O3)(CC/C(/C=N/NC(NC4=CC=C(C)C=C4)=O)=C\CC1)[H])[H])(O2)[H]
Molecular Formula
C23H27N3O4
Molecular Weight
409.48
Shipping Conditions
Cool pack
Storage Temperature
-20°C
Available Sizes
Curated Selection
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