Anticancer agent 71

Product Specifications

CAS Number

2453228-45-8

Target

Others|||Apoptosis|||PARP

Related Pathways

Others|||Chromatin/Epigenetic|||Apoptosis|||DNA Damage/DNA Repair

Bioactivity

Anticancer agent 71 (Compound 4b) is a potent anticancer agent that arrests the cell cycle at the G2/M phase and induces apoptosis by upregulating Bax, Ikb-?, and cleaved PARP, while downregulating Bcl-2 expression levels.

Smiles

N(C(NC1=CC(C(F)(F)F)=C(Cl)C=C1)=O)C2=CC(=NC(N)=N2)C3=CC=CC=C3

Molecular Formula

C18H13ClF3N5O

Molecular Weight

407.78

Shipping Conditions

Cool pack

Storage Temperature

-20°C

Available Sizes

Curated Selection

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