Anticancer agent 71
Product Specifications
CAS Number
2453228-45-8
Target
Others|||Apoptosis|||PARP
Related Pathways
Others|||Chromatin/Epigenetic|||Apoptosis|||DNA Damage/DNA Repair
Bioactivity
Anticancer agent 71 (Compound 4b) is a potent anticancer agent that arrests the cell cycle at the G2/M phase and induces apoptosis by upregulating Bax, Ikb-?, and cleaved PARP, while downregulating Bcl-2 expression levels.
Smiles
N(C(NC1=CC(C(F)(F)F)=C(Cl)C=C1)=O)C2=CC(=NC(N)=N2)C3=CC=CC=C3
Molecular Formula
C18H13ClF3N5O
Molecular Weight
407.78
Shipping Conditions
Cool pack
Storage Temperature
-20°C
Available Sizes
Curated Selection
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