Tubulin polymerization-IN-30
Product Specifications
CAS Number
2521560-46-1
Target
Microtubule Associated|||Others
Related Pathways
Cytoskeletal Signaling|||Others
Bioactivity
Tubulin polymerization-IN-30 (compound 6e) is a potent inhibitor of tubulin polymerization that disrupts intracellular microtubule organization and arrests the cell cycle at the G2/M phase. Tubulin polymerization-IN-30 exhibits high potency against cancer cell lines HeLa, SGC-7901, and A549, with IC 50 values of 0.403, 2.16, and 2.21 ?M, respectively.
Smiles
C(=O)(C=1N(C(C)=NN1)C2=CC=CC=C2)N3CCN(CC3)C4=CC(OC)=CC(OC)=C4
Molecular Formula
C22H25N5O3
Molecular Weight
407.47
Shipping Conditions
Cool pack
Storage Temperature
-20°C
Available Sizes
Curated Selection
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