SKI-I

Product Specifications

CAS Number

306301-68-8

Target

Apoptosis|||Others|||S1P Receptor

Related Pathways

GPCR/G Protein|||Others|||Apoptosis

Bioactivity

SKI-I is a potent and selective inhibitor of human sphingosine kinase (SK), with an IC50 of 1.2 ?M for ST-hSK, and also inhibits hERK2 (IC50 = 11 ?M) . SKI-I induces apoptosis in tumor cell lines.

Smiles

Oc1ccc2ccccc2c1\C=N\NC(=O)c1cc([nH]n1)-c1ccc2ccccc2c1

Molecular Formula

C25H18N4O2

Molecular Weight

406.44

Shipping Conditions

Cool pack

Storage Temperature

-20°C

Available Sizes

Curated Selection

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