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SKI-I

Product Specifications

CAS Number

306301-68-8

Target

Apoptosis, Others, S1P Receptor

Related Pathways

GPCR/G Protein, Others, Apoptosis

Bioactivity

SKI-I is a potent and selective inhibitor of human sphingosine kinase (SK), with an IC50 of 1.2 μM for ST-hSK, and also inhibits hERK2 (IC50 = 11 μM) . SKI-I induces apoptosis in tumor cell lines.

Smiles

Oc1ccc2ccccc2c1\C=N\NC(=O)c1cc([nH]n1)-c1ccc2ccccc2c1

Molecular Formula

C25H18N4O2

Molecular Weight

406.44

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

Available Sizes

Frequently Asked Questions

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