Dolutegravir
Product Specifications
CAS Number
1051375-16-6
Target
HIV Protease
Related Pathways
Proteases/Proteasome, Microbiology/Virology
Purity
0.9975
Bioactivity
Dolutegravir (GSK1349572) (IC50=2.7 nM), a two-metal-binding HIV integrase inhibitor, exhibits medium activity against raltegravir-resistant signature mutants Y143R, Q148K, N155H, and G140S/Q148H.
Smiles
C[C@@H]1CCO[C@H]2Cn3cc(C(=O)NCc4ccc(F)cc4F)c(=O)c(O)c3C(=O)N12
Molecular Formula
C20H19F2N3O5
Molecular Weight
419.38
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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