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BACE1/2-IN-1

Product Specifications

CAS Number

2671036-34-1

Target

Beta Amyloid, Beta-Secretase, Others

Related Pathways

Neuroscience, Others

Bioactivity

BACE1/2-IN-1 (compound 34) is an effective BACE1 and BACE2 inhibitor with IC50 values of 0.01 and 0.0053 μM, respectively. It exhibits a lower Pgp efflux ratio, improved passive permeability, and decreased metabolic stability in liver microsomes.

Smiles

C(OC[C@H]1[C@H](C)C1)(C)(C)[C@H]2[C@]([C@@]34[C@@](CN(C3)C=5N=CC=CN5)(CSC(N)=N4)[H])(C2)[H]

Molecular Formula

C21H31N5OS

Molecular Weight

401.57

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

Available Sizes

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