BACE1/2-IN-1
Product Specifications
CAS Number
2671036-34-1
Target
Beta Amyloid|||Beta-Secretase|||Others
Related Pathways
Neuroscience|||Others
Bioactivity
BACE1/2-IN-1 (compound 34) is an effective BACE1 and BACE2 inhibitor with IC50 values of 0.01 and 0.0053 ?M, respectively. It exhibits a lower Pgp efflux ratio, improved passive permeability, and decreased metabolic stability in liver microsomes.
Smiles
C(OC[C@H]1[C@H](C)C1)(C)(C)[C@H]2[C@]([C@@]34[C@@](CN(C3)C=5N=CC=CN5)(CSC(N)=N4)[H])(C2)[H]
Molecular Formula
C21H31N5OS
Molecular Weight
401.57
Shipping Conditions
Cool pack
Storage Temperature
-20°C
Available Sizes
Curated Selection
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