HGGPPS-IN-1
Product Specifications
CAS Number
1429012-38-3
Target
Others|||Apoptosis
Related Pathways
Others|||Apoptosis
Bioactivity
HGGPPS-IN-1 is an analogue of C-2-substituted thienopyrimidine-based bisphosphonates (C2-ThP-BPs) . HGGPPS-IN-1 has an effective inhibitory effect on human geranyl geranyl pyrophosphate synthase (hGGPPS) . HGGPPS-IN-1 can selectively induce apoptosis of multiple myeloma (MM) cells. HGGPPS-IN-1 showed anti-myeloma activity in vivo.
Smiles
N(C(P(=O)(O)O)P(=O)(O)O)C1=C2C(=NC(=N1)C3=CC=CC=C3)SC=C2
Molecular Formula
C13H13N3O6P2S
Molecular Weight
401.27
Shipping Conditions
Cool pack
Storage Temperature
-20°C
Available Sizes
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