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HGGPPS-IN-1

Product Specifications

CAS Number

1429012-38-3

Target

Others|||Apoptosis

Related Pathways

Others|||Apoptosis

Bioactivity

HGGPPS-IN-1 is an analogue of C-2-substituted thienopyrimidine-based bisphosphonates (C2-ThP-BPs) . HGGPPS-IN-1 has an effective inhibitory effect on human geranyl geranyl pyrophosphate synthase (hGGPPS) . HGGPPS-IN-1 can selectively induce apoptosis of multiple myeloma (MM) cells. HGGPPS-IN-1 showed anti-myeloma activity in vivo.

Smiles

N(C(P(=O)(O)O)P(=O)(O)O)C1=C2C(=NC(=N1)C3=CC=CC=C3)SC=C2

Molecular Formula

C13H13N3O6P2S

Molecular Weight

401.27

Shipping Conditions

Cool pack

Storage Temperature

-20°C

Available Sizes

Curated Selection

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