SKLB0565
Product Specifications
CAS Number
2414607-10-4
Target
Microtubule Associated, Others, Apoptosis
Related Pathways
Apoptosis, Cytoskeletal Signaling, Others
Bioactivity
SKLB0565 is an effective inhibitor of tubulin. SKLB0565 significantly inhibited the proliferation of colorectal cancer cells with IC50 of 0.012 - 0.081 μ M. SKLB0565 induces G2/M phase arrest and mitochondria-mediated endogenous apoptosis. SKLB0565 destroys the microtubule formation of HUVECs cells and inhibits cell migration.
Smiles
N(CC1=C(CC)C=C(CC)NC1=O)C2=C3C(N(C=N3)C4CCCC4)=NC(Cl)=N2
Molecular Formula
C20H25ClN6O
Molecular Weight
400.91
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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