BMT-090605 hydrochloride
Product Specifications
CAS Number
2231664-45-0
Target
Serine/threonin kinase|||Others|||AAK1 (AP2 associated kinase 1)
Related Pathways
Others|||Metabolism|||Neuroscience|||Cell Cycle/Checkpoint
Bioactivity
BMT-090605 hydrochloride is an effective and selective inhibitor of connexin-2 associated kinase 1 (AAK1) (IC50=0.6 nM) . BMT-090605 hydrochloride inhibits BMP-2 induced protein kinase (BIKE) (IC50=45 nM) and cyclin G-related kinase GAK (IC50=60 nM) . BMT-090605 hydrochloride shows anti-injury activity. BMT-090605 hydrochloride has research value in neuropathic pain.
Smiles
Cl.CC(C)C[C@H](N)COc1cc2n(C)c(=O)c3c(C)nccc3c2cc1C#N
Molecular Formula
C21H25ClN4O2
Molecular Weight
400.91
Shipping Conditions
Cool pack
Storage Temperature
-20°C
Available Sizes
Curated Selection
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