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Topo I/COX-2-IN-1

Product Specifications

Target

Others, Apoptosis, Prostaglandin Receptor, Topoisomerase

Related Pathways

Apoptosis, GPCR/G Protein, Others, DNA Damage/DNA Repair, Immunology/Inflammation

Bioactivity

Topo I/COX-2-IN-1 (1H-30) is a potent Topo I/COX-2 inhibitor with IC50 values of 0.24 μM for COX-2 and 4.42 μM for Topo I. It induces apoptosis and inhibits cancer cell migration, demonstrating anti-cancer activity.

Molecular Formula

C21H18ClFN2O3

Molecular Weight

400.83

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

Available Sizes

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