B-Raf IN 9
Product Specifications
CAS Number
2477725-18-9
Target
Raf, Apoptosis, Others
Related Pathways
Others, Apoptosis, MAPK
Bioactivity
B-Raf IN 9 (compound 8b) is an effective B-Raf inhibitor (IC50=24.79 nM) that blocks the cell cycle at the G2/M phase, induces apoptosis, and exhibits potent anti-tumor activity on human prostate cancer PC-3 cells (IC50=7.83 μM) .
Smiles
O=C1N(N=C(CC1)C2=CC=C(NC(NC3=CC=CC=C3)=S)C=C2)C4=CC=CC=C4
Molecular Formula
C23H20N4OS
Molecular Weight
400.5
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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