Yhhu-3792
Product Specifications
CAS Number
2097826-24-7
Target
Gamma-secretase, Others
Related Pathways
Proteases/Proteasome, Stem Cells, Neuroscience, Others
Bioactivity
Yhhu-3792 activates Notch signaling pathway and promotes the expression of Hes3 and Hes5. Yhhu-3792 enhanced the self-renewal ability of neural stem cells (NSCs), expanded the NSC pool and promoted endogenous neurogenesis in the dentate gyrus (DG) of the hippocampus in mice. Yhhu-3792 can improve the situational and spatial memory ability of mice. Yhhu-3792 has research potential in DG dysfunction related to memory impairment.
Smiles
COc1cccc(Oc2cccc3nc(Nc4ccc(cc4)C(C)C)nc(N)c23)c1
Molecular Formula
C24H24N4O2
Molecular Weight
400.47
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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