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Yhhu-3792

Product Specifications

CAS Number

2097826-24-7

Target

Gamma-secretase|||Others

Related Pathways

Proteases/Proteasome|||Stem Cells|||Neuroscience|||Others

Bioactivity

Yhhu-3792 activates Notch signaling pathway and promotes the expression of Hes3 and Hes5. Yhhu-3792 enhanced the self-renewal ability of neural stem cells (NSCs), expanded the NSC pool and promoted endogenous neurogenesis in the dentate gyrus (DG) of the hippocampus in mice. Yhhu-3792 can improve the situational and spatial memory ability of mice. Yhhu-3792 has research potential in DG dysfunction related to memory impairment.

Smiles

COc1cccc(Oc2cccc3nc(Nc4ccc(cc4)C(C)C)nc(N)c23)c1

Molecular Formula

C24H24N4O2

Molecular Weight

400.47

Shipping Conditions

Cool pack

Storage Temperature

-20°C

Available Sizes

Curated Selection

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