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PD-1/PD-L1-IN-14

Product Specifications

CAS Number

2499965-12-5

Target

PD-1/PD-L1, Others

Related Pathways

Cell Cycle/Checkpoint, Apoptosis, Immunology/Inflammation, Others

Bioactivity

PD-1/PD-L1-IN-14 (compound 17) is an inhibitor of PD-1/PD-L1 interaction (IC50=27.8 nM) that promotes PD-L1 dimerization, endocytosis, and degradation.

Smiles

CC1=C(C=2OC(NC3=CC(CNCCO)=CC=C3)=NN2)C=CC=C1C4=CC=CC=C4

Molecular Formula

C24H24N4O2

Molecular Weight

400.47

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

Available Sizes

Frequently Asked Questions

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