RKI-1447 dihydrochloride
Product Specifications
CAS Number
1782109-09-4
Target
Others, Apoptosis, ROCK
Related Pathways
Cytoskeletal Signaling, Stem Cells, Apoptosis, Cell Cycle/Checkpoint, Others
Bioactivity
RKI 1447 dihydrochloride is an effective and selective ROCK inhibitor (ROCK1 IC50=14.5 nM, ROCK2 IC50=6.2 nM) . RKI 1447 dihydrochloride can inhibit the growth of colorectal cancer cells and promote cell apoptosis.
Smiles
Cl.Cl.Oc1cccc(CNC(=O)Nc2nc(cs2)-c2ccncc2)c1
Molecular Formula
C16H16Cl2N4O2S
Molecular Weight
399.29
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
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