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(E/Z) -BIO-acetoxime

Product Specifications

CAS Number

740841-15-0

Target

GSK-3|||Others|||CDK

Related Pathways

PI3K/Akt/mTOR signaling|||Cell Cycle/Checkpoint|||Stem Cells|||Others

Bioactivity

(E/Z) - BIO-acetoxime is effective and selective GSK-3 ?/? Inhibitors. For GSK-3 ?/?, CDK5/p25, CDK2/cyclin A and CDK1/cyclin B, IC50 are 10nM, 2.4 ?M, 4.3 ? M, 63 ? M, respectively.

Smiles

N(OC(C)=O)=C1C(NC=2C1=CC=CC2)=C3C=4C(NC3=O)=CC(Br)=CC4

Molecular Formula

C18H12BrN3O3

Molecular Weight

398.21

Shipping Conditions

Cool pack

Storage Temperature

-20°C

Available Sizes

Curated Selection

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