Tubulin polymerization-IN-26
Product Specifications
CAS Number
2490291-68-2
Target
Apoptosis, Others, Microtubule Associated
Related Pathways
Others, Apoptosis, Cytoskeletal Signaling
Bioactivity
Tubulin polymerization-IN-26 (compound 12h) is a chemical compound that inhibits the polymerization of microtubulin by binding to the colchicine binding site, with an IC50 value of 4.64 μM. It can induce apoptosis and inhibit cell metastasis, making it a valuable compound for researching lung cancer [1].
Smiles
N(C(/C=C/C1=C(OCC)C=CC=C1)=O)C2=C(C=CC=C2)C=3NC=4C(N3)=CC=C(C)C4
Molecular Formula
C25H23N3O2
Molecular Weight
397.47
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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