DNA-PK-IN-4
Product Specifications
CAS Number
2722645-10-3
Target
Others|||DNA-PK
Related Pathways
DNA Damage/DNA Repair|||PI3K/Akt/mTOR signaling|||Others
Bioactivity
DNA-PK-IN-4 (WO2021209055A1, compound 27), an imidazolinone derivative compound, is a highly effective inhibitor of DNA-PK, specifically targeting DNA-PKcs activity. By inhibiting DNA-PKcs, the compound significantly impairs tumor DNA repair mechanisms and triggers apoptosis in cells. With its potential application in cancer research, DNA-PK-IN-4 holds promise for further investigation [1].
Smiles
O=C1N(C=2C(N1C)=CN=C(NC3=C(C)C=C(C(NC)=O)C=C3)N2)C4CCOCC4
Molecular Formula
C20H24N6O3
Molecular Weight
396.44
Shipping Conditions
Cool pack
Storage Temperature
-20°C
Available Sizes
Curated Selection
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