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HCAIX-IN-8

Product Specifications

CAS Number

2414633-40-0

Target

Others, Carbonic Anhydrase

Related Pathways

Others, Metabolism

Bioactivity

HCAIX-IN-8 (compound 7i) is a highly potent and selective inhibitor of hCAIX with an IC50 value of 0.024 μM, and also inhibits CAII and CAVA with IC50 values of 1.99 μM and 1.10 μM, respectively. It exhibits anti-proliferative effects, low toxicity, reduces epithelial-to-mesenchymal transitions, promotes apoptosis, and inhibits cell migration and colonization potential [1].

Smiles

C(OC1=C(OC)C=C(/C=C/C(O)=O)C=C1)C2=CN(N=N2)C3=CC(N(=O)=O)=CC=C3

Molecular Formula

C19H16N4O6

Molecular Weight

396.35

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

Available Sizes

Frequently Asked Questions

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