HCAIX-IN-8
Product Specifications
CAS Number
2414633-40-0
Target
Others, Carbonic Anhydrase
Related Pathways
Others, Metabolism
Bioactivity
HCAIX-IN-8 (compound 7i) is a highly potent and selective inhibitor of hCAIX with an IC50 value of 0.024 μM, and also inhibits CAII and CAVA with IC50 values of 1.99 μM and 1.10 μM, respectively. It exhibits anti-proliferative effects, low toxicity, reduces epithelial-to-mesenchymal transitions, promotes apoptosis, and inhibits cell migration and colonization potential [1].
Smiles
C(OC1=C(OC)C=C(/C=C/C(O)=O)C=C1)C2=CN(N=N2)C3=CC(N(=O)=O)=CC=C3
Molecular Formula
C19H16N4O6
Molecular Weight
396.35
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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