CM398
Product Specifications
CAS Number
1121931-70-1
Target
Others, Sigma receptor
Related Pathways
GPCR/G Protein, Others
Bioactivity
CM398 is an orally active chemical compound that acts as a highly selective ligand for the sigma-2 receptor (K i =0.43 nM), demonstrating a significant ratio of selectivity between sigma-1 and sigma-2 receptors (1000-fold) . Moreover, CM398 exhibits notable affinity towards dopamine (K i =32.90 nM) and serotonin transporters (K i =244.2 nM) . In addition, CM398 has shown promising efficacy as an anti-inflammatory analgesic in a mouse model of inflammatory pain induced by formalin [1].
Smiles
COc1cc2CCN(CCCCn3c4ccccc4n(C)c3=O)Cc2cc1OC
Molecular Formula
C23H29N3O3
Molecular Weight
395.49
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
Frequently Asked Questions
More Discoveries
Explore Other Products
Browse additional items from our catalog
IRBAMLPDPK1AP535200UL 200 µL
Rabbit Anti PDPK1 Polyclonal Affinity Purified (PBS with 0.02% sodium azide, 0.5% BSA and 50% glycerol, pH7.4) (Western Blot,IHC-p,ELISA) 200ul
Sign In for Pricing
View Details MBS6387477-01 0.1 mL
NR2F2 (COUP Transcription Factor 2, COUP-TF2, Apolipoprotein A-I Regulatory Protein 1, ARP-1, COUP Transcription Factor II, COUP-TF II, Nuclear Receptor Subfamily 2 Group F Member 2, ARP1, TFCOUP2) (MaxLight 650)
Sign In for Pricing
View Details