Carbonic anhydrase inhibitor 14
Product Specifications
CAS Number
2410402-75-2
Target
CDK, Others, Carbonic Anhydrase
Related Pathways
Metabolism, Others, Cell Cycle/Checkpoint
Bioactivity
Carbonic anhydrase inhibitor 14 (Compound 8b) is a potent CA inhibitor, exhibiting K i values of 1203, 99.7, 9.4, and 27.7 nM against hCA I, hCA II, hCA IX, and hCA XII, respectively. Additionally, it effectively inhibits CDK2 with an IC 50 of 20.3 μM and demonstrates significant antitumor activity [1].
Smiles
N(=N/C1=CC=C(S(N)(=O)=O)C=C1)\C2=C3N(C=C(N3)C4=CC=C(C)C=C4)N=C2N
Molecular Formula
C18H17N7O2S
Molecular Weight
395.44
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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