Orantinib
Product Specifications
CAS Number
252916-29-3
Target
PDGFR, FGFR, VEGFR, Apoptosis
Related Pathways
Apoptosis, Angiogenesis, Tyrosine Kinase/Adaptors
Purity
>99.99%
Bioactivity
Orantinib (NSC 702827), a excellent effective against PDGFR autophosphorylation with Ki of 8 nM, also highly inhibits Flk-1 and FGFR1 trans-phosphorylation. It shows little effect against IGF-1R, Met, Src, Lck, Zap70, Abl and CDK2 and does not suppresses EGFR.
Smiles
Cc1[nH]c(\C=C2/C(=O)Nc3ccccc23)c(C)c1CCC(O)=O
Molecular Formula
C18H18N2O3
Molecular Weight
310.35
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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