Tovinontrine
Product Specifications
CAS Number
2062661-53-2
Target
PDE
Related Pathways
Metabolism
Purity
0.988
Bioactivity
Tovinontrine (IMR-687) (IMR-687) is a potent and selective inhibitor of phosphodiesterase-9 (PDE9), designed to target sickle cell disease treatment. It exhibits high efficacy, with IC 50 values of 8.19 nM and 9.99 nM for PDE9A1 and PDE9A2, respectively [1].
Smiles
C[C@@H]1CN(Cc2ncccn2)C[C@H]1c1cn2c(ncc2c(=O)[nH]1)C1CCOCC1
Molecular Formula
C21H26N6O2
Molecular Weight
394.47
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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