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Tovinontrine

Product Specifications

CAS Number

2062661-53-2

Target

PDE

Related Pathways

Metabolism

Purity

0.988

Bioactivity

Tovinontrine (IMR-687) (IMR-687) is a potent and selective inhibitor of phosphodiesterase-9 (PDE9), designed to target sickle cell disease treatment. It exhibits high efficacy, with IC 50 values of 8.19 nM and 9.99 nM for PDE9A1 and PDE9A2, respectively [1].

Smiles

C[C@@H]1CN(Cc2ncccn2)C[C@H]1c1cn2c(ncc2c(=O)[nH]1)C1CCOCC1

Molecular Formula

C21H26N6O2

Molecular Weight

394.47

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

Available Sizes

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