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Anticancer agent 63

Product Specifications

CAS Number

2529657-32-5

Target

Caspase|||Apoptosis|||Bcl-2 Family|||Others

Related Pathways

Proteases/Proteasome|||Others|||Apoptosis

Bioactivity

Anticancer agent 63 (compound 3h) exhibits significant cytotoxic activity against multiple cancer cell lines, including SW480, HeLa, A549, and MCF-7, with IC50 values of 4.9, 11.5, 9.4, and 3.4 ?M, respectively, after 24 hours of treatment. It induces apoptosis in MCF-7 cells by down-regulating Bcl-2 expression and up-regulating IL-2 and Caspase-3 expression, and also demonstrates antioxidative properties [1].

Smiles

C(C(NCCC[Se]C(F)(F)F)=O)(C)C1=CC=C(CC(C)C)C=C1

Molecular Formula

C17H24F3NOSe

Molecular Weight

394.33

Shipping Conditions

Cool pack

Storage Temperature

-20°C

Available Sizes

Curated Selection

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