M1002
Product Specifications
CAS Number
823830-85-9
Target
HIF/HIF Prolyl-Hydroxylase|||HIF
Related Pathways
Chromatin/Epigenetic|||Metabolism|||Angiogenesis
Purity
0.9998
Bioactivity
M1002 is a hypoxia-inducible factor-2 (HIF-2) agonist that enhances the affinity of HIF-2alpha and ARNT for transcriptional activation. It alters the Tyr2 conformation of the HIF-2alpha PAS-B structural domain and acts synergistically with inhibitors of the prolyl hydroxylase structural domain (PHD) .
Smiles
FC(F)(F)C1=CC(=CC(NC2=NS(=O)(=O)C3=CC=CC=C23)=C1)C(F)(F)F
Molecular Formula
C15H8F6N2O2S
Molecular Weight
394.29
Shipping Conditions
Cool pack
Storage Temperature
-20°C
Available Sizes
Curated Selection
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