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HIV-1 inhibitor-35

Product Specifications

CAS Number

2416971-32-7

Target

HIV Protease|||Others

Related Pathways

Microbiology/Virology|||Others|||Proteases/Proteasome

Bioactivity

HIV-1 inhibitor-35 (compound 74) is a highly potent inhibitor of the HIV-1 virus, exhibiting EC50 values of 80 nM and 70 nM for LTR and CMV, respectively, in HEK293 cells. Additionally, it demonstrates inhibitory activity against HepG2 liver cancer cells, with a CC50 value of 40 nM, and shows promise as a potential HIV-1 latency reversing agent [1].

Smiles

ClC1=CC(N2CCN(C(NC=3SC(Cl)=CN3)=O)CC2)=CN=C1Cl

Molecular Formula

C13H12Cl3N5OS

Molecular Weight

392.69

Shipping Conditions

Cool pack

Storage Temperature

-20°C

Available Sizes

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