PTC-209 hydrobromide
Product Specifications
CAS Number
1217022-63-3
Target
BMI-1, Autophagy
Related Pathways
Cell Cycle/Checkpoint, DNA Damage/DNA Repair, Autophagy
Purity
0.9991
Bioactivity
PTC-209 hydrobromide (PTC-209 HBr) is the hydrobromide salt of PTC-209, which is a potent and selective BMI-1 inhibitor with IC50 of 0.5 μM, and results in irreversible reduction of cancer-initiating cells (CICs) .
Smiles
Br.COC1=CC(Br)=C(NC2=NC(=CS2)C2=C(C)N=C3N=CC=CN23)C(Br)=C1
Molecular Formula
C17H13Br2N5OS·HBr
Molecular Weight
576.1
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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