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PTC-209 hydrobromide

Product Specifications

CAS Number

1217022-63-3

Target

BMI-1, Autophagy

Related Pathways

Cell Cycle/Checkpoint, DNA Damage/DNA Repair, Autophagy

Purity

0.9991

Bioactivity

PTC-209 hydrobromide (PTC-209 HBr) is the hydrobromide salt of PTC-209, which is a potent and selective BMI-1 inhibitor with IC50 of 0.5 μM, and results in irreversible reduction of cancer-initiating cells (CICs) .

Smiles

Br.COC1=CC(Br)=C(NC2=NC(=CS2)C2=C(C)N=C3N=CC=CN23)C(Br)=C1

Molecular Formula

C17H13Br2N5OS·HBr

Molecular Weight

576.1

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

Available Sizes

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