PF-562271 besylate
Product Specifications
CAS Number
939791-38-5
Target
FAK, PYK2, CDK
Related Pathways
Tyrosine Kinase/Adaptors, Cytoskeletal Signaling, Cell Cycle/Checkpoint, Angiogenesis
Purity
0.995
Bioactivity
PF-562271 besylate (PF-00562271 Besylate) is a potent, ATP-competitive, reversible inhibitor of FAK with IC50 of 1.5 nM, ~10-fold less potent for Pyk2 than FAK and >100-fold selectivity against other protein kinases, except for some CDKs.
Smiles
OS(=O)(=O)c1ccccc1.CN(c1ncccc1CNc1nc(Nc2ccc3NC(=O)Cc3c2)ncc1C(F)(F)F)S(C)(=O)=O
Molecular Formula
C21H20F3N7O3S·C6H6O3S
Molecular Weight
665.66
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
Frequently Asked Questions
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