HP1328
Product Specifications
CAS Number
2245074-20-6
Target
Others|||FLT
Related Pathways
Tyrosine Kinase/Adaptors|||Angiogenesis|||Others
Bioactivity
HP1328 is a highly effective inhibitor of FLT3 receptor tyrosine kinase with a specific focus on FLT3/ITD mutation. It belongs to the benzoimidazole scaffold-based compound family. Significantly reducing the leukemia burden, HP1328 effectively extends the survival of mice afflicted with FLT3/ITD leukemia [1].
Smiles
N(CC1=CC(OC)=C(OCCO)C=C1)C=2C=C3C(N(C=N3)C4=CC=CC=C4)=CC2
Molecular Formula
C23H23N3O3
Molecular Weight
389.45
Shipping Conditions
Cool pack
Storage Temperature
-20°C
Available Sizes
Curated Selection
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