CDK8-IN-11
Product Specifications
CAS Number
2839338-28-0
Target
CDK, Wnt/beta-catenin
Related Pathways
Cell Cycle/Checkpoint, Cytoskeletal Signaling, Stem Cells
Purity
0.9974
Bioactivity
CDK8-IN-11 is a selective and potent CDK8 inhibitor that shows antiproliferative activity in colon cancer cell lines, inhibiting WNT/β-catenin activation and TCF family transcriptional activity, inducing G1-phase arrest in HCT-116 cells, useful for colon cancer research.
Smiles
O=C(NC1=CC=C(OC2=CN=C(N)C=C2)C=C1)NC3=CC=CC(=C3)C(F)(F)F
Molecular Formula
C19H15F3N4O2
Molecular Weight
388.34
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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