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CDK8-IN-11

Product Specifications

CAS Number

2839338-28-0

Target

CDK|||Wnt/beta-catenin

Related Pathways

Cell Cycle/Checkpoint|||Cytoskeletal Signaling|||Stem Cells

Purity

0.9974

Bioactivity

CDK8-IN-11 is a selective and potent CDK8 inhibitor that shows antiproliferative activity in colon cancer cell lines, inhibiting WNT/?-catenin activation and TCF family transcriptional activity, inducing G1-phase arrest in HCT-116 cells, useful for colon cancer research.

Smiles

O=C(NC1=CC=C(OC2=CN=C(N)C=C2)C=C1)NC3=CC=CC(=C3)C(F)(F)F

Molecular Formula

C19H15F3N4O2

Molecular Weight

388.34

Shipping Conditions

Cool pack

Storage Temperature

-20°C

Available Sizes

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