What is the catalog number for Dyrk1A-IN-5?

The catalog number for Dyrk1A-IN-5 is T61739.

What sizes are available for Dyrk1A-IN-5?

Dyrk1A-IN-5 is available in the following size(s): 25 mg, 50 mg, 100 mg.

How many pack sizes does Dyrk1A-IN-5 come in?

Dyrk1A-IN-5 is available in 3 different pack sizes.

Is Dyrk1A-IN-5 in stock?

Dyrk1A-IN-5 is currently made to order / not held in immediate stock. Contact us for lead time.

Who manufactures Dyrk1A-IN-5?

Dyrk1A-IN-5 is manufactured by Molfinity.

What is the estimated delivery time for Dyrk1A-IN-5?

Estimated delivery time for Dyrk1A-IN-5 is approximately 10 business day(s), depending on your location.

Dyrk1A-IN-5

Product Specifications

CAS Number

1685235-41-9

Target

Others, DYRK

Related Pathways

Tyrosine Kinase/Adaptors, Others, Cell Cycle/Checkpoint

Bioactivity

Dyrk1A-IN-5 (compound 5j) is a highly potent and selective DYRK1A inhibitor with an IC50 of 6 nM, reducing the phosphorylation of Thr434 in SF3B1 dose-dependently (IC50 = 0.5 μM) and inhibiting tau phosphorylation at Thr212 (IC50 = 2.1 μM), making it valuable for Down syndrome research [1].