HDAC6/8/BRPF1-IN-1
Product Specifications
CAS Number
2484255-65-2
Target
HDAC, Others
Related Pathways
Others, Chromatin/Epigenetic, DNA Damage/DNA Repair
Bioactivity
HDAC6/8/BRPF1-IN-1 is a dual inhibitor targeting HDAC6, HDAC8, and the bromodomain and PHD finger containing protein 1 (BRPF1) . It exhibits inhibitory activity against HDAC1, HDAC6, and HDAC8 with IC50 values of 797 nM, 344 nM, and 908 nM, respectively, and inhibits BRPF1 with a Kd value of 175.2 nM. This compound is utilized in cancer research [1].
Smiles
CN1C=2C(=CC(NS(=O)(=O)C3=CC=C(C(NO)=O)C=C3)=CC2)C=C(C)C1=O
Molecular Formula
C18H17N3O5S
Molecular Weight
387.41
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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