Topoisomerase I inhibitor 4
Selected Variant
T61717-01
Size: 25 mg
Product Specifications
CAS Number
2485135-31-5
Target
Others, Topoisomerase
Related Pathways
DNA Damage/DNA Repair, Others
Bioactivity
Topoisomerase I inhibitor 4 (compound 7a) is a potent inhibitor of topoisomerase I activity, effectively inhibiting the proliferation of various cancer cell lines, including HepG2, A549, MCF-7, and HeLa, with IC50 values of 1.20 μM, 2.09 μM, 1.56 μM, and 1.92 μM, respectively. Thus, Topoisomerase I inhibitor 4 holds promise for cancer research applications [1].
Smiles
O=C1N2C(C=3C(C2)=CC=4C(C3)=CC=CC4)=NC=5C1=CC(F)=C(C5)N6CCNCC6
Molecular Formula
C23H19FN4O
Molecular Weight
386.42
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
Price
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