Trk-IN-8

Trk-IN-8, a powerful TRK inhibitor, demonstrates excellent potency against TRKAa, TRKA (G595R), and TRKC (G623R) with IC50 values of 0.42 nM, 0.89 nM, and 1.5 nM, respectively (WO2021115401A1, compound 3) [1].