COX-2-IN-14
Product Specifications
CAS Number
2428387-48-6
Target
Others, COX
Related Pathways
Others, Neuroscience, Immunology/Inflammation
Bioactivity
COX-2-IN-14 (compound 2a) is a highly potent and selective inhibitor of COX-2 (cyclooxygenase-2), binding strongly at the active site of the COX-2 co-crystal. Demonstrating remarkable in vivo anti-inflammatory activity, COX-2-IN-14 effectively reduces ear edema and myeloperoxidase (MPO) activity in mice [1].
Smiles
CNC.CCOC(=O)c1[nH]c(=O)c(cc1C(=O)c1ccc(cc1)[N+]([O-])=O)C#N
Molecular Formula
C18H18N4O6
Molecular Weight
386.364
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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