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MIF-IN-6

Product Specifications

CAS Number

2582758-61-8

Target

MIF, Others

Related Pathways

Others, Immunology/Inflammation

Bioactivity

MIF-IN-6 (compound 2d) is an effective inhibitor of macrophage migration inhibitory factor (MIF), with an IC50 of 1.4 μM and a Ki value of 0.96 μM. It effectively reduces MIF-induced ERK phosphorylation and impedes A549 cell proliferation [1].

Smiles

C(NCC1=CN(N=N1)C2=CC(F)=C(O)C=C2)(=O)C=3NC=4C(C3)=CC(Cl)=CC4

Molecular Formula

C18H13ClFN5O2

Molecular Weight

385.78

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

Available Sizes

Frequently Asked Questions

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