MIF-IN-6
Product Specifications
CAS Number
2582758-61-8
Target
MIF, Others
Related Pathways
Others, Immunology/Inflammation
Bioactivity
MIF-IN-6 (compound 2d) is an effective inhibitor of macrophage migration inhibitory factor (MIF), with an IC50 of 1.4 μM and a Ki value of 0.96 μM. It effectively reduces MIF-induced ERK phosphorylation and impedes A549 cell proliferation [1].
Smiles
C(NCC1=CN(N=N1)C2=CC(F)=C(O)C=C2)(=O)C=3NC=4C(C3)=CC(Cl)=CC4
Molecular Formula
C18H13ClFN5O2
Molecular Weight
385.78
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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