Welcome to GenPrice! Check out our latest updates.

Shopping Cart (0)

Your cart is empty

Add some products to get started!

Osunprotafib

Product Specifications

CAS Number

2489404-97-7

Target

STAT, JAK, Phosphatase

Related Pathways

Angiogenesis, Chromatin/Epigenetic, Tyrosine Kinase/Adaptors, Stem Cells, JAK/STAT signaling, Metabolism

Purity

>99.99%

Bioactivity

Osunprotafib (ABBV-CLS-484) is a potent, orally bioavailable PTP1B/PTPN2 inhibitor in clinical trials for solid tumors. [1] Osunprotafib (ABBV-CLS-484) stimulates the tumor microenvironment and promotes natural killer cell and CD8 T cell function and enhances T cell anti-tumor immunity by enhancing JAK-STAT signaling and reducing T cell dysfunction. [2]

Smiles

CC(C)CCN[C@@H]1CCc2cc(O)c(N3CC(=O)NS3(=O)=O)c(F)c2C1

Molecular Formula

C17H24FN3O4S

Molecular Weight

385.45

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

Available Sizes

Frequently Asked Questions

More Discoveries

Explore Other Products

Browse additional items from our catalog

Rabbit Polyclonal SH2D1A Antibody [Alexa Fluor 700]
NBP2-99726AF700 0.1 mL

Rabbit Polyclonal SH2D1A Antibody [Alexa Fluor 700]

Sign In for Pricing
View Details
CSNK1G2 Mouse Monoclonal Antibody [Clone ID: LBI5F4]
AMM15676VCF 100 µg

CSNK1G2 Mouse Monoclonal Antibody [Clone ID: LBI5F4]

Sign In for Pricing
View Details
Human Anthrax Toxin Receptor 2 (ANTXR2) ELISA Kit
DL-ANTXR2-Hu-01 48 Tests

Human Anthrax Toxin Receptor 2 (ANTXR2) ELISA Kit

Sign In for Pricing
View Details
Human Anthrax Toxin Receptor 2 (ANTXR2) ELISA Kit
DL-ANTXR2-Hu-02 96 Tests

Human Anthrax Toxin Receptor 2 (ANTXR2) ELISA Kit

Sign In for Pricing
View Details
PXMP3 AAV Vector (Mouse) (CMV)
38238104 1 µg

PXMP3 AAV Vector (Mouse) (CMV)

Sign In for Pricing
View Details
Med11 CRISPR Activation Plasmid (h)
sc-409522-ACT 20 µg

Med11 CRISPR Activation Plasmid (h)

Sign In for Pricing
View Details