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PARP1-IN-10

Product Specifications

CAS Number

2494001-21-5

Target

Others, PARP, Apoptosis

Related Pathways

Chromatin/Epigenetic, Apoptosis, Others, DNA Damage/DNA Repair

Bioactivity

PARP1-IN-10 (compound 12c) is a highly potent and non-cytotoxic PARP1 inhibitor with an in vitro IC50 value of 50.62 nM, effectively inducing cell cycle arrest at the G2/M phase and apoptosis, while significantly augmenting the cytotoxic effects of temozolomide (TMZ) [1].

Smiles

C(=C1C(=O)N(C)C(=O)N(C)C1=O)C2=CC=C(OCC(=O)N3CCCCC3)C=C2

Molecular Formula

C20H23N3O5

Molecular Weight

385.41

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

Available Sizes

Frequently Asked Questions

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